Thames Valley Police have closed the A421 by the Bottle Dump Roundabout and Whaddon Road after a collision.
Police officers are currently on the scene after a collision occurred earlier this evening (10/03).
Thames Valley Police advise locals to avoid this road and find alternative routes.
It is unknown if anyone was hurt or when the road will reopen.
UPDATE (10/03 at 21:53):
Thames Valley Police have tweeted to inform local drivers that the A421 has now reopened and thanked the public for their cooperation.
