A section of the M1 is set to be closed from 9pm on Saturday night until 9am.
A section of the M1 Northbound is set to close between 9pm and 9am on Saturday 9th April.
Drivers are being warned to plan ahead when travelling next weekend ahead of the closures, as it may disrupt late or early travelling.
The closure will take place between Junction 14 - Junction 15, with a full carriageway closure between 9pm and 9am Saturday.
Newport Pagnell Services will also be closed along with Junction 14 entry slip.
Junction 13 to 14 will close on lanes 2, 3 and 4.
National Highways say: "Roadworks affect all journeys which is why it is important they are completed as quickly and safely as possible. Our overnight closures are under constant review and we aim to open the road earlier than the times displayed wherever possible.
"Please be considerate of residents living along the diversion routes when travelling during these closures. Closures can only be installed once traffic flows are at their lowest."